Menoprogen, a TCM Herbal Formula for Menopause, Increases Endogenous E₂ in an Aged Rat Model of Menopause by Reducing Ovarian Granulosa Cell Apoptosis

Figure 1

The effects of Menoprogen and Progynova on ovarian GC ultrastructure. (a) Euchromatins were observed in the normal control group, and all cell organs were morphologically normal. (b) In the NAM group, GC nuclei exhibited smaller cell bodies, concentrated chromatins, and apoptotic cells. (c) GCs in the Menoprogen group also had increased euchromatins as compared with the NAM control rats, cellular organs were increased, and there were no apoptotic bodies observed. (d) In the Progynova group the GCs displayed primarily euchromatin and a few apoptotic bodies were observed.

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