Research Article
Menoprogen, a TCM Herbal Formula for Menopause, Increases Endogenous E2 in an Aged Rat Model of Menopause by Reducing Ovarian Granulosa Cell Apoptosis
Figure 3
Effects of Menoprogen on expression of Bcl-2 and Bax proteins. (a) There was higher Bcl-2 protein expression in the normal control group (b) and lower Bcl-2 expression in the untreated NAM group. (c) The expression of Bcl-2 was increased in NAM rats after treatment with Menoprogen. (d) When compared with the Menoprogen treated rats, the expression of Bcl-2 was higher in the Progynova treated rats. (e) In addition, the normal control group showed a weak expression of Bax protein, (f) while the untreated NAM group showed strongly positive expression of Bax. (g, h) The expression of Bax protein decreased in both the Menoprogen treated (g) and the Progynova treated (h) groups (200x).
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