Menoprogen, a TCM Herbal Formula for Menopause, Increases Endogenous E₂ in an Aged Rat Model of Menopause by Reducing Ovarian Granulosa Cell Apoptosis

Figure 4

The in vitro effect of Menoprogen-medicated serum on GC ultrastructure. (a) The GCs showed a normal ultrastructure in normal control rats. (b) In the MPG-medicated serum group, both cellular organelles and secretary granule were enriched. (c) In the NAM group, it was observed that chromatin within nucleus was in shifting and there was marginal aggregation, endocytoplasmic reticulum became vacuolated, and the number of secretary granules was decreased.

(a)

(b)

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