Myoinositol Attenuates the Cell Loss and Biochemical Changes Induced by Kainic Acid Status Epilepticus

Figure 4

Representative Western blot autoradiograph of P2 mitochondrial-membrane fraction for VDAC-1, (a) and (c), and mean relative amounts of VDAC-1 (b) from the hippocampus of 6 different groups of rats. (a) and (c) Each lane was derived from a single sample. Lanes 1–6: CON + SAL; lanes 7–12: CON + MI; lanes 13–18: CON + DIAZ; lanes 19–24: KA + SAL; lanes 25–30: KA + MI; and lanes 31–36: KA + DIAZ. (b) Error bars represent the standard errors of the means. KA + SAL and KA + DIAZ groups significantly exceed all control groups as well as KA + MI group (). The mean amount of VDAC-1 in the KA + MI group is not significantly different from the means of any of the control groups and the means of control groups differ significantly from each other. Groups of rats: 1: CON + SAL; 2: CON + MI; 3: CON + DIAZ; 4: KA + SAL; 5: KA + MI; and 6: KA + DIAZ.

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