Phosphoprotein Phosphatase 1 Is Required for Extracellular Calcium-Induced Keratinocyte Differentiation

Figure 6

Inhibition of PI3K, PLC, or PKC activity blocks calcium-induced PIP5K1α dephosphorylation. Cultured human keratinocytes were treated with inhibitors for PI3K, PLC, and PKC for 72 hours and then with calcium for 5 min. Cells were harvested and then analyzed by western analysis.