Amlodipine Ameliorates Ischemia-Induced Neovascularization in Diabetic Rats through Endothelial Progenitor Cell Mobilization

Figure 5

Effects of amlodipine and perindopril on neovascularization in diabetic rats after AMI. (a) Capillary formation in infarct border zone as stained by CD31 (red). (b) Blood vessel formation in heart as stained by vWF (green). (c) Small artery formation in heart as stained by α-SMA (red); each picture was comprised of four fields. Nuclei were stained by DAPI (blue). Blood vessel density was expressed as the number of capillaries per field ( in each group). and . Scale bar = 50 μm for (a and b) and scale bar = 200 μm for (c).

(a)

(b)

(c)