Amlodipine Ameliorates Ischemia-Induced Neovascularization in Diabetic Rats through Endothelial Progenitor Cell Mobilization

Table 1

Characteristics of diabetic and nondiabetic rats.

	Nondiabetics	Diabetics
	20	80
Weight (g)
Week 0	233.15 7.71	228.98 8.35	0.25
Week 4	361.19 24.38	431.14 27.42	<0.01
Week 8	452.6 21.9	448.9 37.8	0.67
Glucose (mM)
FBG week 5	4.13 0.43	16.14 2.61	<0.01
PBG week 5	10.56 1.24	30.42 3.31	<0.01
Triglycerides (mM)	0.762 0.165	2.369 1.497	0.002
Cholesterol (mM)	1.54 0.30	2.21 0.62	0.003
Fasting insulin; (μIU/mL)	34.304 4.822	73.402 9.734	0.004
ISI	−4.931 0.736	−7.622 0.763	<0.01

All plasma determinations were performed in the fasting state. Lipid and fasting insulin were measured at week 4, whilst fasting and postprandial blood glucose were measured 5 days after STZ (week 5). FBG: fasting blood glucose, PBG: postprandial blood glucose, and ISI: insulin sensitivity index.