BioMed Research International / 2016 / Article / Tab 2 / Review Article
The Role of 18 F-FDG PET/CT and MRI in Assessing Pathological Complete Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer: A Systematic Review and Meta-Analysis Table 2 Characteristics of the patients and explanation method of the two evaluating methods (18 F-FDG PET/CT and MRI).
Author County Year Initial clinical stage Histology subtype Receptor status Parameter of PET/CT Parameter of MRI Reconstruction or not Image interpretation Cut-off value of PET/CT Cut-off value of MRI Pengel et al. [23 ] Netherlands 2014 II ( ) III ( ) IVa ( ) IDC ( ) ILC ( ) Others ( ) HER-2(+) ( ) ER(+)/PR(−) ( ) Triple(−) ( ) ROI + SUV ROI + diameter Yes NR Reduction > 50% Reduction > 75% ( ) Kim et al. [22 ] Korea 2014 II ( ) III ( ) IVa ( ) IDC ( ) ILC ( ) MC ( ) NR ROI + SUV ROI + diameter ROI + volume Yes Blind Reduction > 60.1% Reduction > 50% ( ) Reduction > 68.9% ( ) Tateishi et al. [21 ] Japan 2012 Ia ( ) II ( ) III ( ) IDC ( ) ILC ( ) ER(+) ( ) PR(+) ( ) HER-2(+) ( ) ROI + SUV ROI + Kep Yes NR Reduction > 50% Reduction > 30% ( ) Park et al. [20 ] Korea 2011 NR IDC ( ) MC ( ) ER(+) ( ) PR(+) ( ) ROI + SUV ROI + diameter Yes Blind Reduction > 50% Reduction > 30% ( ) Choi et al. [19 ] Korea 2010 II, III IDC ( ) ILC ( ) MC ( ) Other ( ) ER(+) ( ) PR(+) ( ) HER-2(+) ( ) ROI + pSUV ROI + diameter NR Blind Reduction > 50% Reduction > 30% ( ) Chen et al. [18 ] USA 2004 LABC IDC ( ) ILC ( ) MC ( ) ER(+) ( ) PR(+) ( ) HER-2(+) ( ) ROI + SUV ROI + diameter Yes Blind Reduction > 50% Reduction > 30% ( )
LABC: local advanced breast cancer. IDC: invasive ductal carcinomas. ILC: invasive lobular carcinomas. MC: metaplastic carcinoma. ER: estrogen receptor. PR: progesterone receptor. ROI: region of interest. : diameter. : volume. NR: not reported.