The Role of ¹⁸F-FDG PET/CT and MRI in Assessing Pathological Complete Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer: A Systematic Review and Meta-Analysis

Table 2

Characteristics of the patients and explanation method of the two evaluating methods (¹⁸F-FDG PET/CT and MRI).

Author	County	Year	Initial clinical stage	Histology subtype	Receptor status	Parameter of PET/CT	Parameter of MRI	Reconstruction or not	Image interpretation	Cut-off value of PET/CT	Cut-off value of MRI
Pengel et al. [23]	Netherlands	2014	II (); III (); IVa ()	IDC (); ILC (); Others ()	HER-2(+) (); ER(+)/PR(−) (); Triple(−) ()	ROI + SUV	ROI + diameter	Yes	NR	Reduction > 50%	Reduction > 75% ()
Kim et al. [22]	Korea	2014	II (); III (); IVa ()	IDC (); ILC (); MC ()	NR	ROI + SUV	ROI + diameter; ROI + volume	Yes	Blind	Reduction > 60.1%	Reduction > 50% (); Reduction > 68.9% ()
Tateishi et al. [21]	Japan	2012	Ia (); II (); III ()	IDC (); ILC ()	ER(+) (); PR(+) (); HER-2(+) ()	ROI + SUV	ROI + Kep	Yes	NR	Reduction > 50%	Reduction > 30% ()
Park et al. [20]	Korea	2011	NR	IDC (); MC ()	ER(+) (); PR(+) ()	ROI + SUV	ROI + diameter	Yes	Blind	Reduction > 50%	Reduction > 30% ()
Choi et al. [19]	Korea	2010	II, III	IDC (); ILC (); MC (); Other ()	ER(+) (); PR(+) (); HER-2(+) ()	ROI + pSUV	ROI + diameter	NR	Blind	Reduction > 50%	Reduction > 30% ()
Chen et al. [18]	USA	2004	LABC	IDC (); ILC (); MC ()	ER(+) (); PR(+) (); HER-2(+) ()	ROI + SUV	ROI + diameter	Yes	Blind	Reduction > 50%	Reduction > 30% ()

LABC: local advanced breast cancer.
IDC: invasive ductal carcinomas.
ILC: invasive lobular carcinomas.
MC: metaplastic carcinoma.
ER: estrogen receptor.
PR: progesterone receptor.
ROI: region of interest.
: diameter.
: volume.
NR: not reported.