Pacemaker Created in Human Ventricle by Depressing Inward-Rectifier K⁺ Current: A Simulation Study

Figure 6

Snapshots of excitation wave emerging and propagating across the ventricular slice. (a) = 890,673 ms; the excitation is emerging. (b) = 890,675 ms; the wave is conducting to Purkinje fiber. (c) = 890,700 ms; the wave is propagating to VMs. (d) = 890,800 ms; the excitation is propagating in the slice. (e) = 890,900 ms; a slow repolarization state of the tissue. (f) = 891,000 ms; a rapid repolarization state of the slice. (g) = 891,120 ms, the end of the repolarization.

(a)

(b)

(c)

(d)

(e)

(f)

(g)