Comparison of Neuroprotective Effect of Bevacizumab and Sildenafil following Induction of Stroke in a Mouse Model

Figure 1

TTC (2,3,5-triphenyltetrazolium chloride) staining of MCAO infarcted brain tissue from mice treated with saline (control, first column), sildenafil (2nd column), and bevacizumab (3rd and 4th columns). Infarcted tissue is pale while healthy tissue is pink. It is evident that the mice treated with bevacizumab (immediate and late) have the largest amount of healthy tissue, indicating a neuroprotective effect. Each line represents different animal.