NLRP3 Activation Was Regulated by DNA Methylation Modification during Mycobacterium tuberculosis Infection

Figure 6

Methylation status of GAPDH promoter region during Mtb infection. Genomic DNA of THP-1 cells was extracted 24 h after Mtb infection or not. The methylation levels of TSS 1500 (a), TSS 200 (b), and 5′ UTR (c) were detected by Illumina Infinium 450K bead arrays. TSS stands for transcription start site of NLRP3.

(a)

(b)

(c)