Corneal Dendritic Cell Density Is Associated with Subbasal Nerve Plexus Features, Ocular Surface Disease Index, and Serum Vitamin D in Evaporative Dry Eye Disease

Table 4

Association of serum vitamin D with OSDI score, corneal dendritic cell density, and corneal subbasal nerve plexus features in EDE patients.

	Serum vitamin D level
		value
OSDI score
OSDI—total	−0.332	0.0095
OSDI—discomfort	−0.375	0.0032
OSDI—vision	−0.289	0.025
Dendritic cells
Total cells (cells/mm^2)	−0.184	0.1589
DCs with dendrites (cells/mm^2)	−0.322	0.0122
DCs without dendrites (cells/mm^2)	−0.099	0.45
Subbasal nerve plexus
CNFL (length in mm/mm^2)	−0.004	0.9749
CNFD (major nerves/mm^2)	0.037	0.777
CNFW (average nerve fiber width/mm^2)	−0.083	0.5267
CTBD (branch points/mm^2)	−0.094	0.4742
CNBD (number of branches/mm^2)	−0.007	0.96
CNFA (total nerve fiber area/mm^2)	−0.011	0.9334

OSDI: ocular surface disease index; DCs: dendritic cells; CNFL: corneal nerve fiber length; CNFD: corneal nerve fiber density; CNFW: corneal nerve fiber width; CTBD: corneal total branch density; CNBD: corneal nerve branch density; CNFA: corneal nerve fiber area; – Spearman correlation coefficient.