Research Article

Clinical Outcome and Prognostic Factors of Intensity-Modulated Radiotherapy for T4 Stage Nasopharyngeal Carcinoma

Table 1

Characteristics of 110 patients with T4 stage NPC.

Patient characteristicsNumber of patients (%)

Age (y)
 Range17–69
 Median44.5
Gender
 Male87 (79.1)
 Female23 (20.9)
N stage
 N0-135 (31.8)
 N2-375 (68.2)
GTVnx (cc)
 Range22.37–246.10
 Median77.27
GTVln (cc)
 Range0–180.15
 Median14.1
IMRT replanning
 No63 (57.3)
 Yes47 (42.7)
Chemotherapy
 Concurrent 75 (68.2)
 Induction plus concurrent 35 (31.8)
Targeted therapy
 No83 (75.5)
 Yes27 (24.5)
Metastasis to RLN
 No13 (11.8)
 Yes97 (88.2)
Cervical nodal necrosis
 No68 (61.8)
 Yes42 (38.2)

GTVnx, gross tumor volume of the nasopharynx; GTVln, gross tumor volume of the lymph nodes; IMRT, intensity-modulated radiotherapy; RLN, retropharyngeal lymph nodes.