Vitamin A Inhibits Development of Dextran Sulfate Sodium-Induced Colitis and Colon Cancer in a Mouse Model

Figure 1

(a) Intracellular lipid droplets in mucosal subepithelial myofibroblasts of the distal segment of the colon. No lipid droplets were observed in a subepithelial myofibroblast from the colonic crypt base of a vitamin A-deficient mouse (upper) in contrast to detection of lipid droplets (arrow) in that of a vitamin A-supplemented mouse (lower) as assessed by electron microscopy. (b) Significant difference of intracellular lipid droplets in mucosal subepithelial myofibroblasts at the crypt base between two groups (Chi-squared test).

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