The Occurrence of Genetic Alterations during the Progression of Breast Carcinoma

Figure 1

The CNV frequency of six candidate genes in the breast carcinoma patients. The CNVs of at least one of the six candidate genes occur in 342 (36%) of 963 cases/patients. The CNV frequencies of the six candidate genes are PIK3CA (5%, 51/963), AKT2 (2%, 22/963), KRAS (3%, 25/963), PTEN (6%, 55/963), ErbB2 (13%, 121/963), and CCND1 (16%, 153/963).