Application of PK/PD Modeling in Veterinary Field: Dose Optimization and Drug Resistance Prediction

Figure 2

Antimicrobial PK and PD parameters in relation to MIC; the most useful PK parameters are the area under the plasma concentration time curve (AUC) from 0 times to 24 h, the maximum plasma concentration () achieved, and time () during which concentration exceeds a defined threshold. The most useful PD parameter is the minimum inhibitory concentration (MIC).