Distribution of Triamcinolone Acetonide after Intravitreal Injection into Silicone Oil-Filled Eye

Figure 5

Distance from the TA droplet to the bottom of silicone oil bubble after injection. The dots in the graph represent the distance between the bottom of the TA droplet and the bottom of the silicone oil bubble along the time after injections. The 3 different colours represent 3 independent experiments performed on 3 different pig eyes. 0.1 mL TA suspension was injected into the pig eyes in each experiment. Similar to the real case scenario during postvitrectomy drug injection, the insertion sites of the angiocath tip vary among 3 experiments, resulting in slightly different kinetics of the TA droplet. The insertion site for the 1st experiment is lower than the other two, resulting in a shorter sinking time. The insertion site of the 3rd experiment is closer to the lens, resulting in a slow initial dropping speed as the TA droplet slides down along the lens before sinking straight.