Research Article

A Long-Acting BMP-2 Release System Based on Poly(3-hydroxybutyrate) Nanoparticles Modified by Amphiphilic Phospholipid for Osteogenic Differentiation

Table 2

Characterization of BPC-PHB NPs prepared using different BPCs and B-PHB NPs prepared using pure BMP-2 without phospholipids, respectively ().

SamplesSize (nm)PDIZeta potential (mV)EE (%)

PHB NPs242.1 ± 5.20.125 ± 0.012−25.21 ± 2.19
B-PHB NPs251.4 ± 8.10.155 ± 0.015−12.52 ± 1.5412.53 ± 1.62
BPC-PHB NPs253.4 ± 7.10.143 ± 0.018−22.42 ± 2.1477.18 ± 6.39