Research Article
WWOX CNV-67048 Functions as a Risk Factor for Epithelial Ovarian Cancer in Chinese Women by Negatively Interacting with Oral Contraceptive Use
Table 1
Frequency distributions of selected variables among EOC cases and controls.
| | Variables | Case ()
(%) | Control ()
(%) | |
| | Age (years) | | | | | ≤55 | 277 (50.46) | 303 (53.06) | 0.382 | | >55 | 272 (49.54) | 268 (46.94) | | Age at menarche (years) | | | | | <15 | 211 (53.55) | 257 (46.73) | 0.039 | | ≥15 | 183 (46.45) | 293 (53.27) | | Unclear | 155 (—) | 21 (—) | | Number of births | | | | | 0 | 16 (2.91) | 11 (1.93) | <0.001 | | 1–3 | 409 (74.50) | 490 (85.81) | | ≥4 | 124 (22.59) | 70 (12.26) | | Menstrual history | | | | | Premenopause | 152 (27.69) | 131 (22.94) | 0.068 | | Menopause | 397 (72.31) | 440 (77.06) | | Oral contraceptive use | | | | | Never | 414 (82.31) | 399 (75.86) | 0.039 | | Seldom | 56 (11.13) | 78 (14.83) | | Often | 33 (6.56) | 49 (9.32) | | Unclear | 46 (—) | 45 (—) | | Family history of cancer | | | | | Yes | 40 (7.29) | 38 (6.65) | 0.678 | | No | 509 (92.71) | 533 (93.35) | | Smoking status | | | | | Ever | 68 (12.39) | 54 (9.46) | 0.116 | | Never | 481 (87.61) | 517 (90.54) | | Pack-years smoked | | | | | ≥20 | 36 (6.56) | 18 (3.15) | 0.029 | | <20 | 32 (5.83) | 36 (6.30) | | 0 | 481 (87.61) | 517 (90.54) | | Alcohol intake | | | | | Ever | 34 (6.19) | 49 (8.58) | 0.127 | | Never | 515 (93.81) | 522 (91.42) | | Staging | | | | | I + II | 43 (7.84) | | | | III | 420 (76.50) | | | | IV | 86 (15.66) | | |
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values for a test.
Statistical analysis excluded subjects with unclear or unknown data.
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