Research Article
Combinatorial Antitumor Effect of Rapamycin and β-Elemene in Follicular Thyroid Cancer Cells
Table 1
Treatment of
β-elemene could reverse the imbalance of Treg/Th17 in the mouse spleen induced by rapamycin (mean ± SD,
).
| | | Group | | | Control | Rapamycin
5 mg/kg | β-elemene
50 mg/kg | Rapamycin 5 mg/kg + β-elemene 50 mg/kg |
| | Treg/Th17 | 2.2 ± 0.2 | 5.8 ± 0.6# | 1.1 ± 0.3# | 3.4 ± 1.1 | | Treg/CD4+ (%) | 7.6 ± 0.8 | 12.2 ± 1.3# | 4.7 ± 0.7# | 10.1 ± 2.8 | | Th17/CD4+ (%) | 3.6 ± 0.4 | 2.1 ± 0.2# | 4.4 ± 1.3 | 2.8 ± 0.9 | | CD4+ T (%) | 25.4 ± 3.1 | 22.9 ± 4.3 | 27.7 ± 4.5 | 26.6 ± 5.3 |
|
|
versus control group; versus rapamycin group.
|
