An Interoperability Platform Enabling Reuse of Electronic Health Records for Signal Verification Studies

Table 1

Terminology mapping resources that are utilized in the SALUS Framework.

Source system	Target system	Number of mappings	Mapping resource
MedDRA	SNOMED-CT	10,648	OntoADR of the PROTECT project, manual improvement of UMLS mapping by PROTECT experts [73]
ICD-9-CM	SNOMED-CT	16,819	OMOP Vocabulary, created manually by experts
ICD-10-CM	SNOMED-CT	59,122	OMOP Vocabulary, created manually by experts
SNOMED-CT	ICD-10	27,166	CrossMap, a collaborative project by IHTSDO and WHO
ICD-10-GM	ICD-10	12,318	Identical codes in both systems
ICD-9-CM	SNOMED-CT	43,086	BioPortal, manual review by SALUS experts before inclusion
ICD-10-CM	SNOMED-CT	45,022	BioPortal, manual review by SALUS experts before inclusion