Inhibition of DNA Topoisomerase Type II<i>α</i> (TOP2A) by Mitoxantrone and Its Halogenated Derivatives: A Combined Density Functional and Molecular Docking Study

<div>D, D4, D9, and D10 interactions with surrounding residues of TOP2A generated by LigPlus.</div>

BioMed Research International

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Figure 3

Figure 3: Inhibition of DNA Topoisomerase Type II<i>α</i> (TOP2A) by Mitoxantrone and Its Halogenated Derivatives: A Combined Density Functional and Molecular Docking Study 

Figure 3 | Inhibition of DNA Topoisomerase Type IIα (TOP2A) by Mitoxantrone and Its Halogenated Derivatives: A Combined Density Functional and Molecular Docking Study 