Cancerous Inhibitor of PP2A Silencing Inhibits Proliferation and Promotes Apoptosis in Human Multiple Myeloma Cells

Figure 1

CIP2A expression following CIP2A knockdown. ((a) and (b)) CIP2A mRNA expression level in RPMI-8226 (a) and NCI-H929 (b) cells after transfection of indicated concentrations of si-CIP2A or si-Scr, as detected by qRT-PCR. Data are expressed as mean ± SD. < 0.05. (c) CIP2A protein expression after 100 nM si-CIP2A or si-Sci transfection, as determined by western blotting. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) served as a loading control.

(a)

(b)

(c)