Cancerous Inhibitor of PP2A Silencing Inhibits Proliferation and Promotes Apoptosis in Human Multiple Myeloma Cells

Figure 3

Effect of CIP2A knockdown on multiple myeloma cell apoptosis. (a) Representative image of a flow cytometry scatterplot of apoptotic RPMI-8226 and NCI-H929 cells labeled with fluorescein isothiocyanate (FITC) and propidium iodide [13] and sorted 72 h after transfection with si-CIP2A or si-Scr. (b) Quantitative analysis of early apoptotic cells after transfection with si-CIP2A or si-Scr. Data are expressed as mean ± SD. < 0.05. (c) The cleavage of PARP detected by western blot. CF: cleaved fragment.

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