Research Article

Cancerous Inhibitor of PP2A Silencing Inhibits Proliferation and Promotes Apoptosis in Human Multiple Myeloma Cells

Figure 7

The scheme illustrating the mechanism by which knockdown CIP2A induces apoptosis and antiproliferation including the counteraction of IGF-1 and PP2A in myeloma cells. Blue arrows indicate activation. Red T-bars indicate suppression.