The Role of ^99mTc-Annexin V Apoptosis Scintigraphy in Visualizing Early Stage Glucocorticoid-Induced Femoral Head Osteonecrosis in the Rabbit

Figure 1

Histological images demonstrating methylprednisolone-induced femoral head necrosis. (a) Representative H&E stained section of a femoral head, 8 weeks after methylprednisolone administration, showing destruction of the bone structure (2 rabbits were examined). (b) Representative H&E stained section of a femoral head section from a control rabbit treated with saline (2 rabbits were examined). (c) TUNEL assay of a femoral head, 8 weeks after methylprednisolone administration. Apoptotic cells (indicated by arrows) are stained brown. (d) TUNEL assay of a femoral head from a control rabbit treated with saline.

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