Research Article

Liver Stiffness Measurement in Psoriasis: Do Metabolic or Disease Factors Play the Important Role?

Table 1

Demographic data based on the presence of high liver stiffness measurement (LSM > 7 kPa).

All patientsLSM ≤ 7 kPaLSM > 7 kPa
()()()

Age (years)49.2 ± 14.048.7 ± 14.153.4 ± 12.70.182
Male75 (45.5)65 (44.2)10 (55.6)0.454
Body mass index (kg/m2)24.8 ± 4.724.0 ± 4.030.77 ± 5.7<0.0001
Waist circumference (cm)87.0 ± 12.385.0 ± 10.7104.1 ± 12.0<0.0001
Diabetes mellitus31 (18.8)22 (15)9 (50)0.001
Hypertension55 (33.3)43 (29.3)12 (66.7)0.003
Dyslipidemia88 (53.3)74 (50.3)14 (77.8)0.043
Metabolic syndrome83 (50.3)66 (44.9)17 (94.4)<0.0001
Psoriasis disease-related factors
Duration of disease (years)16.5 ± 12.116.7 ± 12.314.8 ± 10.90.533
PASI score3.0 ± 2.72.8 ± 2.64.2 ± 3.20.042
Severe psoriasis6 (3.6)4 (2.7)2 (11.1)0.130
Psoriatic arthritis35 (21.2)29 (19.7)6 (33.3)0.220
Cumulative dose of MTX
 None57 (34.5)51 (34.7)6 (33.3)0.906
1.5 g69 (41.8)62 (42.2)7 (38.9)
1.5 g39 (23.6)34 (23.1)5 (27.8)

LSM: liver stiffness measurement; PASI: psoriasis area and severity index; and MTX: methotrexate; mean ± SD; (%).