Research Article

Sequence- and Structure-Based Functional Annotation and Assessment of Metabolic Transporters in Aspergillus oryzae: A Representative Case Study

Table 2

List of manually curated transporter genes and functions in unambiguous function group.

Name of transporter geneTCIDName of transporter function

Class 1: channels and pores

AO0900230005691.A.1.7.1Outward-rectifier potassium channel
AO0900380003141.A.11.3.2Ammonium transporter
AO0900030014021.A.35Magnesium transporter
AO0901200001411.A.35.5.1Magnesium transporter
AO0901200002141.A.56.1.4Copper transporter
AO0900110003291.A.8.8.8Aquaporin
AO0900230008951.B.8.1.1Voltage-dependent anion channel porin

Class 2: electrochemical potential-driven transporters

AO0900030000502.A.1.7.1L-fucose permease
AO0900120006232.A.1.8.5Nitrate transporter
AO0900100001352.A.100.1.3Iron-regulated transporter
AO0900100002292.A.17.2.2Proton-dependent oligopeptide transporter
AO0900260008282.A.19.4.4Sodium/potassium/calcium exchanger
AO0900090006372.A.2.6.1Alpha-glucoside permease
AO0900030014042.A.20Phosphate transporter
AO0900120009012.A.20.2.2Phosphate transporter
AO0901030002742.A.22.3.2Sodium and chloride dependent GABA transporter
AO0900090004052.A.29.1.3Mitochondrial adenine nucleotide translocator
AO0900050001142.A.3.10.2Amino acid transporter
AO0900090006362.A.36.1.12Sodium/hydrogen exchanger
AO0900050000192.A.39.3.1Allantoin permease
AO0900050004552.A.40.5.1Purine permease
AO0900030004432.A.41.2.7H+/nucleoside cotransporter
AO0900030009202.A.47.2.2Phosphate transporter
AO0900260004322.A.49.1.3Chloride channel
AO0900050000262.A.5.1.1Zinc transporter
AO0900110008312.A.5.5.1Zinc transporter
AO0900260004412.A.5.7.1Zinc transporter
AO0900110008172.A.52.1.3Nickel transporter
AO0900030007982.A.53.1.2Sodium-independent sulfate anion transporter
AO0900030011192.A.55.1.1High-affinity metal uptake transporter
AO0900030012332.A.57.3.1Nucleoside transporter
AO0900050013322.A.59.1.1Arsenite transporter
AO0901200002172.A.6.6.5Hydroxymethylglutaryl-CoA reductase
AO09M0000000162.A.63NADH-ubiquinone oxidoreductase
AO0900010007482.A.66Polysaccharide exporter
AO0900100007752.A.7.10.2UDP-xylose/UDP-N-acetylglucosamine transporter
AO0900090004002.A.7.11.1UDP-galactose transporter
AO0900090006882.A.7.13.2GDP-mannose transporter
AO0900260002552.A.72.3.2Potassium transporter
AO0900050014552.A.97.1.4Potassium and hydrogen ion antiporter

Class 3: primary active transporters

AO0900090006513.A.1.201.11Multidrug resistance protein 1
AO0900380003993.A.1.31.1Possible ABC transporter permease for cobalt
AO0900030006883.A.19.1.1Arsenite-translocating ATPase
AO0900100004823.A.2V-type ATPases
AO09M0000000013.A.2.1.3F-type ATPase
AO0900120007973.A.2.2.3V-type ATPase
AO0900380000883.A.3.1.7P-type ATPase
AO0900120007733.A.3.10.1P-type ATPase
AO0900380003223.A.3.2.2P-type ATPase
AO0900050008423.A.3.3.6Plasma membrane proton ATPase
AO09M0000000133.D.1.2.1NADH dehydrogenase
AO09M0000000153.D.1.6.2NADH-ubiquinone oxidoreductase
AO0901020010373.D.2.4.1Proton-translocating transhydrogenase
AO0900100004753.D.3.2.1Cytochrome b-c1 complex subunit Rieske
AO09M0000000143.D.4.8.1Cytochrome oxidase

Names of transporter functions are based on KEGG, PFAM, and UniProt databases.