Next Generation Sequencing Identifies Five Major Classes of Potentially Therapeutic Enzymes Secreted by Lucilia sericata Medical Maggots

Table 4

List of cysteine peptidases in the L. sericata transcriptome database.

Clan	Family	Peptidase type	Peptidase species	MEROPS ID	Number of clusters
CA	C1	Papain	Insect 26/29 kDa peptidase	C01.067	2
			Vitellogenic cathepsin B	C01.068	1
			Bleomycin hydrolase (animal)	C01.084	2
			Papain homologue (Rattus-type)	C01.107	3
			Cathepsin B-like cysteine peptidase (Raphanus sativus)	C01.144	1
			CG12163 protein (D. melanogaster)	C01.A27	2
			CG4847 protein (D. melanogaster)	C01.A28	1
			Nonpeptidase homologues	C01.UNA	3
			Subfamily C1A unassigned peptidases	C01.UPA	1
CA	C2	Calpain 2	Calpain-15	C02.010	1
			Calpain A	C02.14	1
CA	C12	Ubiquitinyl hydrolase-L1	Ubiquitinyl hydrolase-L5	C12.005	1
			CG8445 protein (D. melanogaster)	C12.A09	1
			Family C12 unassigned peptidases	C12.UPW	1
CA	C54	Autophagin-1	CG4428 protein (D. melanogaster)	C54.A04	1
			Family C54 unassigned peptidases	C54.UPW	2
CA	C65	Otubain-1	Otubain-1	C65.001	1
CD	C13	Legumain	Glycosylphosphatidylinositol:protein transamidase	C13.005	2
			Family C13 unassigned peptidases	C13.UPW	2
CD	C14	Caspase-1	Caspase (insect 1)	C14.015	2
			Caspase (insect 2)	C14.016	1
			Caspase DRONC- (D. melanogaster-) type peptidase	C14.019	2
			Caspase DECAY	C14.022	1
			Caspase STRICA (Drosophila sp.)	C14.023	1
			Caspase Dredd	C14.040	1
CE	C48	Ulp1 peptidase	Ulp1 peptidase (Drosophila-type)	C48.024	1
			Family C48 unassigned peptidases	C48.UPW	1
CF	C15	Pyroglutamyl-peptidase	Family C15 unassigned peptidases	C15.UPW	1
PC	C26	Gamma-glutamyl hydrolase	CG32155 protein (D. melanogaster)	C26.A22	2
			Family C26 unassigned peptidases	C26.UPW	1
PD	C46	Hedgehog protein	Hedgehog protein	C46.001	1
			Family C46 unassigned peptidases	C46.UPW	1