Research Article

Next Generation Sequencing Identifies Five Major Classes of Potentially Therapeutic Enzymes Secreted by Lucilia sericata Medical Maggots

Table 7

List of serine peptidases in the L. sericata transcriptome database.

ClanFamilyPeptidase typePeptidase speciesMEROPS IDNumber of clusters

PAS1Chymotrypsin AOvochymase domain 2 (X. laevis)S01.0243
Trypsin alpha (insect) (D. melanogaster)S01.11023
Trypsin zeta (insect) (D. melanogaster)S01.1167
Trypsin eta (insect) (D. melanogaster)S01.1173
Trypsin (mosquito type) (Anopheles gambiae)S01.1302
Chymotrypsin m-type 2 (insect) (Lucilia cuprina)S01.1687
Easter peptidase (D. melanogaster)S01.2016
Melanization peptidase-2 (D. melanogaster)S01.2032
CG4386 peptidase (Sarcophaga peregrina)S01.3162
Prophenoloxidase-activating peptidase (Pacifastacus leniusculus)S01.4132
Persephone peptidase (D. melanogaster)S01.4211
Tequila peptidase (D. melanogaster)S01.4612
DmHtrA2-type peptidase (M. domestica)S01.4762
Proteolytic lectin (Glossina-type) (Glossina fuscipes fuscipes)S01.4933
Grass peptidase (Insecta) (D. melanogaster)S01.5023
TmSPE peptidase (Tenebrio-type) (Tenebrio molitor)S01.5072
CLIP-domain prophenoloxidase activating factor (Cotesia rubecula)S01.9608
Testis-specific protein 50 (H. sapiens)S01.9931
CG34409 protein (D. melanogaster)S01.A231
CG11670 protein (D. melanogaster)S01.A311
CG14780 protein (D. melanogaster)S01.A351
CG8952 protein (D. melanogaster)S01.A362
CG8170 protein (D. melanogaster)S01.A371
CG2105 (D. melanogaster)S01.A512
Sp212 protein (D. melanogaster)S01.A521
CG9733 protein (D. melanogaster)S01.A612
CG7829 protein (D. melanogaster)S01.A621
CG5909 protein (D. melanogaster)S01.A641
CG6048 protein (D. melanogaster)S01.A773
CG6041 protein (D. melanogaster)S01.A784
Trypsin beta (D. melanogaster)S01.A831
CG17571 protein (D. melanogaster)S01.A859
Trypsin lambda (D. melanogaster)S01.A872
CG9676 protein (D. melanogaster)S01.A897
Try29F protein (D. melanogaster)S01.A911
CG17477 protein (D. melanogaster)S01.A921
CG5246 protein (D. melanogaster)S01.A947
CG17475 protein (D. melanogaster)S01.A961
CG5233 protein (D. melanogaster)S01.A972
Jonah 65Aiv (D. melanogaster)S01.B0510
CG7542 protein (D. melanogaster)S01.B073
CG10477 protein (D. melanogaster)S01.B1219
CG6457 protein (D. melanogaster)S01.B132
CG6483 protein (D. melanogaster)S01.B141
CG10472 protein (D. melanogaster)S01.B162
CG11529 protein (D. melanogaster)S01.B221
IP21814 protein (D. melanogaster)S01.B252
Spirit protein (D. melanogaster)S01.B274
CG3700 protein (D. melanogaster)S01.B302
CG1299 protein (D. melanogaster)S01.B3312
CG34350 protein (D. melanogaster)S01.B351
CG4914 protein (D. melanogaster)S01.B411
CG11836 protein (D. melanogaster)S01.B431
CG16821 protein (D. melanogaster)S01.B441
CG32808 protein (D. melanogaster)S01.B471
CG16749 protein (D. melanogaster)S01.B485
CG8299 protein (D. melanogaster)S01.B502
IP10861 protein (D. melanogaster)S01.B611
CG16996 protein (D. melanogaster)S01.B642
CG7142 protein (D. melanogaster)S01.B651
CG11911 protein (D. melanogaster)S01.B688
CG10663-PC, isoform C (D. melanogaster)S01.B774
Subfamily S1A non-peptidase homologuesS01.UNA14

SBS8Subtilisin CarlsbergFurin-1 (arthropod-type)S08.0481
Furin-2 (insect)S08.0491
Site-1 peptidaseS08.0631
KPC2-type peptidaseS08.1092
Subfamily S8A unassigned peptidasesS08.UPA2

SCS9Prolyl oligopeptidaseOmega peptidase (D. melanogaster)S09.0692
CG11034 protein (D. melanogaster)S09.A642
CG11319 (D. melanogaster)S09.A654
Xaa-Pro dipeptidylpeptidaseS09.A731

SCS10Carboxypeptidase YVitellogenic carboxypeptidase-like proteinS10.0032
CG32483 protein (D. melanogaster)S10.A522

SCS28Lysosomal Pro-Xaa carboxypeptidaseLysosomal Pro-Xaa carboxypeptidaseS28.0011
CG9953 protein (D. melanogaster)S28.A102

SFS26Signal peptidase ISignal peptidase (invertebrate)S26.0231
CG11110 protein (D. melanogaster)S26.A091
Subfamily S26A unassigned peptidasesS26.UPA1

SJS16Lon-A peptidaseLon-A peptidaseS16.0012
PIM1 peptidaseS16.0021

SKS14Peptidase ClpPeptidase Clp (type 3)S14.0031

SK S41C-terminal processing peptidase-1C-terminal processing peptidase-1S41.0011
C-terminal processing peptidase-2S41.0042

SKS49Signal peptide peptidase ABSn5_05605 g.p. (Bacillus subtilis)S48.A081

ST S54Rhomboid-1Rhomboid-1 (Diptera)S54.0011
Rhomboid-4 (insect)S54.0122
Cg8972 proteinS54.A121

PCS51Dipeptidase EAlpha-aspartyl dipeptidase (eukaryote)S51.0022