The Effect of Autologous Platelet Lysate Eye Drops: An In Vivo Confocal Microscopy Study

Table 2

Ophthalmological assessment.

		Group A	Group B	value; Gr. A versus Gr. B
OSDI
0	Media (SD)	60.56 (17.69)	60.67 (16.19)	0.821
90	Media (SD)	21.75 (9.86)	53.60 (14.91)	<0.001
value		0.000438	0.059336
Fluorescein score (0–5)
0	Median (IQR)	2 (2)	3 (2.5)	0.17
90	Median (IQR)	1 (2)	3 (2)	<0.001
value		<0.001	0.463
FBUT (sec)
0	Median (IQR)	2 (1)	2 (2)	0.18
90	Median (IQR)	3.5 (2)	2 (1)	<0.001
value		0.005	0.463
BCVA
0	Median (IQR)	8 (4)	6 (3.5)	0.218
90	Median (IQR)	8 (3.5)	6 (3.5)	0.100
value		0.008	0.317
Schirmer test (mm)
0	Median (IQR)	3 (2)	3 (2)	0.989
90	Median (IQR)	3 (1)	3 (0.5)	0.544
value		0.0611	0.328065
Anterior blepharitis (grades 0–4)
0	Median (IQR)	1 (1)	2 (1.5)	0.092
90	Median (IQR)	1 (0.5)	2 (1.5)	0.778
value		0.055	0.109
Posterior blepharitis (grades 0–4)
0	Median (IQR)	1 (1)	1.5 (1)	0.748
90	Median (IQR)	1 (1)	1.5 (1.5)	0.036
value		0.011	0.310
Lipcof (grades 0–3)
0	Median (IQR)	3 (2)	3 (1)	0.419
90	Median (IQR)	3 (2)	3 (1)	0.994
value		1.000	1.000
OPI (>/<1)
0	Median (IQR)	0.29	0.23	0.778
90	Median (IQR)	0.53	0.25	<0.001
value		<0.001	0.245

0 = time 0; 90 = time 90 days; SD = standard deviation; IQR = interquartile range; OSDI = ocular surface disease index; OPI = ocular protection index; FBUT = breakup time; BCVA = best corrected visual acuity.
Statistically significant results.