Antiobesity and Antidiabetes Effects of a Cudrania tricuspidata Hydrophilic Extract Presenting PTP1B Inhibitory Potential

Figure 4

The HFD-fed mice were orally administered CTe (20 or 100 mg/kg) for 3 weeks. Blood was collected from the abdominal vein. (a) Levels of total cholesterol (CHOL), (b) low-density lipoprotein (LDL), (c) high-density lipoprotein (HDL), and (d) triglycerides (TRIG) were analyzed in triplicate using a serum biochemical analyzer. Liver tissue was collected for toxicity test. (e) Aspartate aminotransferase (AST) and (f) alanine aminotransferase (ALT) levels were monitored by clinical chemistry analyzer. Data are presented as the mean ± SD for each group (). Statistical significance was determined by Student’s t-test. versus lean mice; and versus vehicle administered DIO mice.

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