Polymorphisms in DNA Repair Gene XRCC3 and Susceptibility to Breast Cancer in Saudi Females

Table 2

The size of PCR products and fragment generated upon treatment with restriction enzyme for the three SNPs in XRCC3.

XRCC3 SNP	PCR product size (bp)	RE used	Genotype	Fragment sizes (bp) after RE treatment
Thr241Met (rs861539)	231	NlaIII	C>T	CC: 231, 12 bp; CT: 231, 107, 112 & 12 bp; TT: 112, 107 & 12 bp
rs1799794	293	FokI	A>G	AA: 100 & 193 bp; AG: 100, 193 & 293 bp; GG: 293 bp
rs1799796	650	PvuII	A>G	AA: 650 bp; AG: 283, 367 & 650 bp; GG: 283 & 376 bp

RE: restriction endonuclease; SNP: single nucleotide polymorphism; PCR: polymerase chain reaction; bp: base pair.