Therapeutic Effects of CUR-Activated Human Umbilical Cord Mesenchymal Stem Cells on 1-Methyl-4-phenylpyridine-Induced Parkinson’s Disease Cell Model

Figure 3

The expression of TH, DAT, and DA in PD model cells. (a), (b) The Western blot assay results showed that compared with the model group, the expressions of TH and DAT were elevated in the three groups (). The CM-CUR presented a more significant effect compared with the CM-MSC and CUR (), and the effect was more significant in CM-MSC group than the CUR group (). Compared with the control group, the expressions of TH and DAT in the CM-CUR group did not show statistically significant differences, while those in the CM-MSC and CUR groups were significantly lower than those in the control group (). (c) ELISA results showed that CM-CUR, CM-MSC, and CUR could promote the DA secretion of PC12 PD model cells, showing a tendency consistent with the expressions of TH and DAT.

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