Therapeutic Effects of CUR-Activated Human Umbilical Cord Mesenchymal Stem Cells on 1-Methyl-4-phenylpyridine-Induced Parkinson’s Disease Cell Model

Figure 5

Variations of cytokines in the PC12 cells supernatant. Compared with the model group, the IL-6 and IL-10 expressions were elevated in CM-CUR, CM-MSC, and CUR groups () and were most significant in the CM-CUR group (), followed by the CM-MSC and CUR groups. NGF was not expressed in the normal PC12 cells () or the model group (). However, the NGF expression gradually increased after treatment with CM-CUR and CM-MSC ( CM-CUR group versus CM-MSC group). The other cytokines, IL-1β, TNF-α, and IFN-γ, did not show significant differences compared with the control and model groups.