Thrombin Maybe Plays an Important Role in MK Differentiation into Platelets

Figure 5

Thrombin upregulates the expression of CD41b in Meg-01 cells. After 8 h incubation, Meg-01 cells were treated with TPO (80 ng/mL) or thrombin (2 U/mL) for 24 h. (a) The expression of CD41b was assayed by western blot. (b) The expression of CD41b was assayed by flow cytometry (left curves: isotype controls; right curves: antibodies).

(a)

(b)