Thrombin Maybe Plays an Important Role in MK Differentiation into Platelets

Figure 6

Thrombin activates the MAPK/ERK and PI3K/AKT pathways. After 8 h incubation, Meg-01 cells were treated with TPO (80 ng/mL) or thrombin (2 U/mL) for 24 h. (a) The expression of p-ERK was assayed by western blot. (b) The expression of p-AKT was assayed by western blot.

(a)

(b)