Characterization of Enhancing MS Lesions by Dynamic Texture Parameter Analysis of Dynamic Susceptibility Perfusion Imaging

Table 4

ANOVA of texture parameter map (TPM) between enhancing lesions with increased permeability (EL+), enhancing lesions with subtle permeability (EL−), and nonenhancing lesions (NEL) during the inflow, outflow, and reperfusion phase of Gadolinium.

	Inflow phase			Outflow phase			Reperfusion phase
	EL+	EL−	NEL	EL+	EL−	NEL	EL+	EL−	NEL
TPM-ORIG mean	1304,21; (192,25)	1362,85; (255,7)	1355,87; (189,43)	1345,29; (168,13)	1323,95; (278,04)	1315,39; (184,87)	1471,50; (213.27)	1407,63; (249,18)	1371,52; (189,25)
TPM-ORIG SD	81,63; (35,88)	71,61; (25,22)	83,14; (23,29)	105,42; (47,76)	83,22; (24,63)	82,93; (24,08)	(36,23)	(23,29)	(18,79)
TPM-ORIG VAR	8398,22; (7762,47)	6118,53; (3594,62)	7692,92; (4430,34)	14007,4; (13771,01)	7848,0; (4205,91)	7680,92; (4266,07)	(8477,35)	(3449,82)	(2903,61)
TPM-ORIG VARVAR	9,292; (2,135)	2,733; (5,176)	4,189; (1,042)	1,052; (2,371)	2,516; (4,952)	3,222; (7,731)	1,275; (2,783)	3,686; (7,462)	4,476; (1,103)
TPM-DIFF mean	(52,72)	(53,97)	(85,2)	96,31; (76,2)	169,7; (76,13)	134,37; (87,81)	(109,68)	(24,99)	(46,23)
TPM-DIFF SD	63,13; (34,76)	53,11; (25,51)	44,18; (22,47)	(26,98)	(20,25)	(24,36)	(76,73)	(12,4)	(9,42)
TPM-DIFF VAR	5615,45; (5691,76)	4037,2; (3707,4)	2925,68; (3141,22)	(5176,78)	(2875,78)	(3687,26)	(28558,66)	(910,2)	(569,62)
TPM-DIFF VARVAR	362978351; (781954883)	565232636; (1,2519)	81051320; (361085909)	158928026; (352922644)	579771510; (1,4200)	115586359; (491925502)	(20663894)	(1989839)	(7228998)
TPM-SD mean	82,02; (78,91)	61,28; (29,69)	46,59; (20,58)	(41,8)	(21,55)	(23,93)	(57,66)	(13,24)	(11,25)
TPM-SD SD	19,96; (20,99)	12,84; (6,88)	13,69; (12,19)	20,06; (11,41)	15,75; (7,15)	12,86; (6,74)	(21,73)	(2,48)	(2,63)
TPM-SD VAR	894,6; (2044,61)	278,93; (337,1)	383,08; (893,47)	608,14; (70,66)	363,77; (314,13)	244,75; (249,86)	(1880,55)	(45,58)	(45,07)
TPM-SD VARVAR	133699885; (432101281)	14178164; (44203559)	333236; (995759)	43079835; (126417365)	9755466; (21630255)	546108; (2004049)	(5828131)	(1010409)	(82408)
TPM-VAR mean	14218,05; (31070,18)	5783,47; (7305,58)	3360,02; (3458,39)	(13142,85)	(4283,4)	(4019,22)	(19700,63)	(1167,26)	(871,07)
TPM-VAR SD	6809,39; (15272,13)	2386,8; (2847,22)	2130,69; (3203,33)	(5789,93)	(2165,8)	(2061,01)	(11524,87)	(395,44)	(377,58)
TPM-VAR VAR	303820710; (973974129)	23181513,3; (62790956,2)	19406582,6; (57926284,0)	93586953,5; (243511997)	21479750,6; (40452799,7)	11376694,4; (23205702,7)	183622050; (557625048)	618965,14; (840273,06)	407992,02; (832069,7)
TPM-VAR VARVAR	4,156; (1,378)	6,431; (2,477)	4,414; (1,405)	7,405; (2,45)	2,636; (9,942)	1,017; (

Note: values are mean (SD); significant ANOVA results are marked with if and with if and with if .