Research Article
Negative Correlation between miR-200c and Decorin Plays an Important Role in the Pathogenesis of Colorectal Carcinoma
Table 2
Clinical relevance of miR-200c.
| | Number | miRNA expression | value | | | High | Low | |
| Age | | | | 0.42 | >60 | 198 | 108 | 24 | | ≤60 | 31 | 90 | 27 | | Distant metastasis | | | | 1 | 0 | 204 | 107 | 97 | | 1 | 41 | 22 | 19 | | Colon polyps history | | | | | Yes | 105 | 47 | 58 | | No | 133 | 78 | 55 | | Lymphatic invasion | | | | 0.1 | Yes | 127 | 69 | 58 | | No | 101 | 43 | 58 | | Tumor stage | | | | 0.88 | I | 50 | 24 | 26 | | II | 89 | 47 | 42 | | III | 65 | 36 | 29 | | IV | 41 | 22 | 19 | | Neoplasm cancer status | | | | 0.34 | With tumor | 214 | 110 | 104 | | Tumor free | 32 | 13 | 19 | | Number of positive lymph nodes | | | | 0.34 | 2 | 83 | 37 | 46 | | <2 | 160 | 83 | 77 | | Vascular invasion present | | | | 0.35 | Yes | 58 | 29 | 29 | | No | 151 | 63 | 88 | | Overall Survival | | | | 0.0025 | 31 days (median) | 156 | 66 | 90 | | >31 days (median) | 92 | 58 | 34 | |
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indicates that colon polyps history was significantly () related to the expression level of miR-200c.
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