Effect of Glycine, Pyruvate, and Resveratrol on the Regeneration Process of Postischemic Intestinal Mucosa

Table 1

Schema of the experimental groups.

Study group		Applied; kg^−1 BW × h^−1	Ischemia/reperfusion period
Sham	6		0 min/0 min
Ischemia/reperfusion, I/R	8		60 min/300 min
Glycine + I/R	8	15 mg glycine	60 min/300 min
Pyruvate + I/R	8	50 mg sodium pyruvate	60 min/300 min
Resveratrol + I/R	8	40 μg Resveratrol	60 min/300 min

Rats were subjected to mesenteric I/R for 60 min, followed by 300 min of reperfusion. Glycine (15 mg/kg BW × h), sodium pyruvate (50 mg/kg BW × h), or resveratrol (40 µg/kg BW × h) were administered intravenously 30 min after the onset of reperfusion until the end of the observation period. Control animals (±I/R) received the same volume of 0.9% NaCl solution. infused in 7 ml × kg⁻¹ × h⁻¹ 0.9% NaCl.