Predicting Factors for Allogeneic Blood Transfusion and Excessive Postoperative Blood Loss after Single Low-Dosage Intra-Articular Tranexamic Acid Application in Total Knee Replacement
Table 1
Characteristics of the 299 TKRs underwent primary TKR with IA-TXA application during 2013-2014 and risk factors for receiving blood transfusion.
Patients characteristics
Total ()
BT
p value
Received BT ()
No BT ()
Age, year +
69 ± 8
71 ± 9
69 ± 8
0.57
Male gender ■
54 (18)
3 (19)
51 (18)
1.00
Right side ■
145 (48)
10 (63)
135 (48)
0.31
Weight, kg +
65 ± 12
59 ± 13
66 ± 12
Height, cm +
156 ± 8
157 ± 8
155 ± 8
0.48
BMI, kg/m2 +
27.0 ± 4.3
24.0 ± 4.4
27.2 ± 4.3
ASA grading ■
1-2
127 (42)
6 (37)
121 (43)
0.80
3-4
172 (58)
10 (63)
162 (57)
CCI +
3.7 ± 1.0
3.8 ± 1.3
3.7 ± 1.0
0.63
Comorbidities ■
HT
230 (77)
12 (75)
218 (77)
0.79
RA
9 (3)
0 (0)
9 (3)
1.00
Antiplatelet agents usage ■
35 (12)
2 (13)
33 (12)
1.00
OA KL grade 4 ■
197 (67)
12 (75)
185 (65)
0.59
Femorotibial angle, degree +
−5.8 ± 6.4
−6.6 ± 5.9
−5.8 ± 6.4
0.65
Preoperative ROM, degree +
109 ± 19
118 ± 19
109 ± 19
0.08
Preoperative laboratory values +
Hb, g/dL
12.6 ± 1.2
11.1 ± 1.3
12.6 ± 1.1
<0.000
Platelet count, ×103/mm3
273 ± 80
256 ± 68
274 ± 81
0.40
aPTT, second
27.0 ± 2.4
26.8 ± 2.6
27.1 ± 2.4
0.74
INR
1.01 ± 0.06
1.05 ± 0.10
1.01 ± 0.05
Albumin, g/dL
38.7 ± 3.6
36.8 ± 5.3
38.8 ± 3.5
CrCl, ml/min
70.6 ± 23.4
58.1 ± 19.2
71.3 ± 23.4
General anesthesia ■
16 (5)
1 (6)
15 (5)
0.59
Operative time, minute +
80 ± 17
72 ± 9
81 ± 17
0.06
Large prosthesis size ■
85 (28)
4 (25)
81 (29)
1.00
IBL, mL +
47 ± 35
47 ± 36
44 ± 15
0.74
IBL/kg, mL/kg +
0.7 ± 0.5
0.7 ± 0.5
0.8 ± 0.3
0.67
DV, mL +
404 ± 225
550 ± 320
396 ± 216
DV/kg, mL/kg +
6.3 ± 3.5
9.5 ± 3.2
6.1 ± 3.3
THL, g/dL +
1.6 ± 0.5
2.3 ± 1.5
1.6 ± 0.9
ETBL, mL +
196 ± 122
495 ± 136
179 ± 96
<0.000
BT: blood transfusion; +: value presented as mean ± standard deviation; ■: value presented as number of cases (percentage); BMI: body mass index; ASA: American Society of Anesthesiologists; CCI: Charlson Comorbidity Index; HT: hypertension; RA: rheumatoid arthritis; OA: osteoarthritis; KL: Kellgren-Lawrence; ROM: range-of-motion; Hb: hemoglobin; aPTT: activated partial thromboplastin time; INR: international normalized ratio; CrCl: creatinine clearance; IBL: intraoperative blood loss; IBL/kg: intraoperative blood loss per kg; DV: drainage volume; DV/kg: drainage volume per kg; : significant value with .
