Shin’iseihaito (Xinyiqingfeitang) Suppresses the Biofilm Formation of<i> Streptococcus pneumoniae</i> In Vitro

<div>The inhibitory effects of the extracts of each component of Shin’iseihaito on the biofilm formation of<i> S. pneumoniae. S. pneumoniae</i> was treated with or without each extract of the components of Shin’iseihaito and SSHT (500 <i>µ</i>g/mL) for 2 days, and its anti-antibiofilm activity was quantified by crystal violet adsorption by measuring the absorbance at 570 nm. Data shown represent the mean ± SD (<svg height="8.55521pt" id="M14" style="vertical-align:-0.2063904pt" version="1.1" viewbox="-0.0498162 -8.34882 27.8368 8.55521" width="27.8368pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M495 86L479 114C446 82 419 66 409 66C401 66 401 72 406 97C420 166 436 231 453 297C489 435 454 448 428 448C406 448 384 439 354 422C305 394 222 327 161 247H159L183 345C200 415 194 448 173 448C143 448 82 410 23 351L38 325C64 349 95 371 105 371C111 371 116 365 109 336L25 -4L31 -12C50 -4 77 3 107 9C119 69 132 122 145 168C197 254 321 381 370 381C387 381 393 374 378 305L329 95C309 17 320 -12 345 -12C372 -12 430 19 495 86Z" id="g113-111"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="502" vert-adv-y="502"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,10.158,0)"><path d="M535 323V373H52V323H535ZM535 138V188H52V138H535Z" id="g117-34"></path><glyph.data ascent="3473" 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SSHT: Shin’iseihaito extract; AA: the rhizome of<i> Anemarrhena asphodeloides</i>; CH: the rhizome of<i> Cimicifuga heracleifolia</i>; EJ: the leaf of<i> Eriobotrya japonica</i>; GF:<i> Gypsum fibrosum</i>; GJ: the fruit of<i> Gardenia jasminoides</i>; LL: the bulb of<i> Lilium lancifolium</i>; MS: the flower of<i> Magnolia salicifolia</i>; OJ: the tuber of<i> Ophiopogon japonicus</i>; SB: the root of<i> Scutellaria baicalensis.</i></div>

BioMed Research International

fig5

Figure 5

Figure 5: Shin’iseihaito (Xinyiqingfeitang) Suppresses the Biofilm Formation of<i> Streptococcus pneumoniae</i> In Vitro 

BioMed Research International

Shin’iseihaito (Xinyiqingfeitang) Suppresses the Biofilm Formation of Streptococcus pneumoniae In Vitro

Figure 5