Research Article
Pharmacokinetics, Tissue Distribution, and Metabolism Study of Icariin in Rat
Table 3
Matrix effect and extraction recovery for the assay of icariin in plasma and tissue samples (
).
| Matrix | Conc. ng/mL | Matrix effect Mean ± SD (%) | Extraction efficiency Mean ± SD (%) |
| Plasma | 2 | | | 20 | | | 400 | | |
| Liver | 2 | | | 20 | | | 400 | | |
| Heart | 2 | | | 20 | | | 400 | | |
| Spleen | 2 | | | 20 | | | 400 | | |
| Lung | 2 | | | 20 | | | 400 | | |
| Kidney | 2 | | | 20 | | | 400 | | |
| Brain | 2 | | | 20 | | | 400 | | |
| Testicle | 2 | | | 20 | | | 400 | | |
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