Pharmacokinetics, Tissue Distribution, and Metabolism Study of Icariin in Rat

Table 4

Stability of icariin in plasma and tissue samples ().

Matrix	Conc.	Mean ± SD
	ng/mL	Bench-top	Freeze-thaw	Autosampler	Long-term
Plasma	2
	20
	400
Liver	2
	20
	400
Heart	2
	20
	400
Spleen	2
	20
	400
Lung	2
	20
	400
Kidney	2
	20
	400
Brain	2
	20
	400
Testicle	2
	20
	400

At least 1 h at room temperature. At least 3 freeze-thaw cycles. At least 24 h at 4°C. At least 4 weeks at °C.