Research Article
Age-Adjusted D-Dimer in the Prediction of Pulmonary Embolism: Does a Normal Age-Adjusted D-Dimer Rule Out PE?
Table 1
Characteristics of the study population.
| Patient characteristic | No PE ( = 768) | PE ( = 126) |
| Age (years) | 55.5 (17.4) | 58.8 (14.7) | Gender (, %) | | | Female | 440 (57.3%) | 58 (46%) | Male | 328 (42.7%) | 68 (54%) | (mean +/− SD) | 95.4 (4.9) | 94.5 (4.9) | | 92.4 (51.7) | 89.9 (52.4) | | 40.2 (12.1) | 39.8 (12.1) | A-a gradient | 117.2 (145.5) | 132.2 (111.1) | D-Dimer | 1066.7 (2121.7) | 4029 (7037.1) | Wells rule | 3.8 (2.1) | 5.6 (2.5) | Geneva score | 5.8 (2.6) | 7.9 (3.4) | Symptom (, %) | | | CP | 336 (43.7%) | 41 (32.5%) | SOB | 389 (50.6%) | 80 (63.5%) | Unknown | 36 (4.7%) | 5 (4%) | Stasis (, %) | | | | 499 (65.0%) | 77 (61.1%) | + | 262 (34.1%) | 49 (38.9%) | Surgery/fracture (, %) | | | | 683 (88.9%) | 114 (90.5%) | + | 68 (8.9%) | 12 (9.5%) | Signs of DVT (, %) | | | | 681 (88.6%) | 83 (65.9%) | + | 80 (10.4%) | 43 (34.1%) | Hemoptysis (, %) | | | | 737 (95.9%) | 120 (95.2%) | + | 24 (3.1%) | 6 (4.8%) | Cancer (, %) | | | | 554 (72.1%) | 82 (65.1%) | + | 205 (26.6%) | 44 (34.9%) | Unilateral limb pain (, %) | | | | 719 (93.6%) | 97 (77%) | + | 42 (5.5%) | 29 (23%) | Previous DVT/PE (, %) | | | | 664 (86.4%) | 97 (77%) | + | 97 (12.6%) | 29 (23%) | PNA (WBC CXR) (, %) | | | | 610 (79.4%) | 109 (86.5%) | + | 151 (19.7%) | 17 (13.5%) | COPD (PCO2 Wheeze) (, %) | | | | 677 (88.1%) | 116 (92.1%) | + | 83 (10.8%) | 10 (7.9%) | ACS/HF (, %) | | | | 641 (83.5%) | 110 (87.3%) | + | 120 (15.6%) | 16 (12.7%) | Other diagnosis (, %) | | | | 716 (93.2%) | 122 (96.8%) | + | 34 (4.4%) | 3 (2.4%) | Heart rate (, %) | | | ≤100 | 366 (47.6%) | 55 (43.7%) | >100 | 392 (51%) | 71 (56.3%) | SpO2 | | | Under 75 | 96 (12.5%) | 11 (8.7%) | 75–94 | 199 (25.9%) | 33 (26.2%) | 95 or Above | 463 (60.8%) | 82 (65.1%) |
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CP: chest pain; SOB: shortness of breath; PNA: pneumonia; COPD: chronic obstructive pulmonary disease; ACS/HF: acute coronary syndrome/heart failure.
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