Age-Adjusted D-Dimer in the Prediction of Pulmonary Embolism: Does a Normal Age-Adjusted D-Dimer Rule Out PE?
Table 3
Predictive power of Geneva score and its elements.
Data-defined
Odds ratio† (95% CI)
value†
Sensitivity†
Specificity†
Sensitivity + specificity
Geneva score (continuous)
≥7
2.84 (1.93, 4.24)
<0.001
0.64
0.61
1.26
HR > 74
—
1.52 (0.82, 3.08)
0.213
0.91
0.13
1.04
HR ≥ 95
—
1.19 (0.80, 1.77)
0.393
0.65
0.39
1.04
Stasis (+ versus −)
—
1.21 (0.82, 1.78)
0.332
0.39
0.66
1.04
Signs of DVT (+versus −)
—
4.41 (2.84, 6.80)
<0.001
0.34
0.89
1.24
Hemoptysis (+versus −)
—
1.54 (0.56, 3.61)
0.358
0.05
0.97
1.02
Cancer (+versus −)
—
1.45 (0.97, 2.15)
0.069
0.35
0.73
1.08
Unilateral Limb Pain (+versus −)
—
5.12 (3.03, 8.57)
<0.001
0.23
0.94
1.17
Previous DVT/PE (+versus −)
—
2.05 (1.27, 3.23)
0.003
0.23
0.87
1.10
at which probability of PE predicted by logistic regression model equals or first exceeds observed frequency of PE. predictor categorized using data-defined cutoff, where applicable.
