p21-Activated Kinase 4 Promotes Intimal Hyperplasia and Vascular Smooth Muscle Cells Proliferation during Superficial Femoral Artery Restenosis after Angioplasty

Figure 1

PAK4 involved in IH in human superficial femoral artery (SFA). (a) Representation of vascular walls in normal people and patients with H&E staining (magnification ×4, ×10, and ×20, resp.). Normal, human SFA samples collected from normal people. Surgery, human SFA samples collected from patients that underwent percutaneous transluminal angioplasty (PTA) treatment of SFA. The arrows indicated the vascular intima. (b) qRT-PCR analysis of PAK4 mRNA levels in control group (N1–N3) and experimental group (P1–P3). (c) Western blot analysis of PAK4 protein levels in control group (N1–N3) and experimental group (P1–P3). (, data are means ± SD, versus N1).

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