Melanomas and Dysplastic Nevi Differ in Epidermal CD1c+ Dendritic Cell Count

Table 2

Number of dendritic cells in epidermal and dermal compartment of dysplastic nevi and in situ and invasive melanomas.

	Epidermal				Dermal
	Mean	Range	SD		Mean	Range	SD
CD1a
Invasive melanoma	38.24	0–80	21.63	0.2808 (NS)	22.55	0–53	14.79	0.2434 (NS)
In situ melanoma	35.84	15–70	13.25		16.32	3–39	10.85
Dysplastic nevus	43.29	18–74	14.92		15.29	1–43	11.27
All cases	39.23	0–80	17.10		18.03	0–53	12.65
CD1c
Invasive melanoma	7.00	0–36	10.55	0.0003	51.81	6–96	30.79	0.0559 (NS)
In situ melanoma	2.94	0–17	4.96		33.56	0–151	37.21
Dysplastic nevus	13.35	2–45	12.44		40.00	8–172	35.08
All cases	7.92	0–45	10.70		42.24	0–172	34.56
DC-LAMP
Invasive melanoma	0.00	0-0	0.00	0.3588 (NS)	1.26	0–10	2.62	0.2456 (NS)
In situ melanoma	0.00	0-0	0.00		0.77	0–14	3.02
Dysplastic nevus	0.05	0-1	0.22		0.85	0–7	2.01
All cases	0.02	0-1	0.13		0.95	0–14	2.57
DC-SIGN
Invasive melanoma	0.10	0–2	0.45	0.5867 (NS)	11.89	0–39	13.54	0.2495 (NS)
In situ melanoma	0.26	0–5	1.15		4.53	0–26	8.19
Dysplastic nevus	0.00	0-0	0.00		4.24	0–32	7.31
All cases	0.12	0–5	0.69		6.71	0–39	10.34