Directional Transport of a Bead Bound to Lamellipodial Surface Is Driven by Actin Polymerization

Figure 2

(a) The (, ) plots of a bead bound to lamellipodium of the untreated cell. The recording duration was 33 s. (b) The (, ) plots of a bead bound to the glass surface (fixed bead), representing the mechanical drift of the experimental system; the recording duration was 50 s. (c) The MSD plot of the bead moving on lamellipodium (see Section 2.5). The data were the same as that shown in (a); this curve was fit with a quadratic function of the time, t: MSD = 0.002769 + 0.001304t − 0.001659, = 0.999988.

(a)

(b)

(c)